CHARLOTTE, NC
Neuropathy Clinical Trials
Three neuropathy studies are enrolling near Charlotte NC, and they are three unrelated conditions. None of them serves nerve damage from diabetes, which is the commonest cause, and we would rather say so. Compensation is provided for eligible participants.
3
Open Near Charlotte
3
Different Conditions
+/- $100
Per Visit
New here? Read how this page works
First, here is the honest picture. Three studies are open, and they treat three different diseases. So here is how to use this page.
- Find out what is causing yours. Because neuropathy is a word for several different diseases, and the cause decides which studies exist for you.
- Ask for four ordinary blood tests. Notably, vitamin B12, thyroid, kidney function and a blood count explain a real share of unexplained cases.
- If chemotherapy is coming, raise prevention now. In fact, one study here has to start within three days of your first dose.
- Finally, tap the button. Then we check you against every study we track and tell you which ones fit.
Of course, checking never signs you up for anything. You are only seeing where you might fit.
Studies Open Near Charlotte Right Now
Three of them, and they share only a word. So read what each one is actually for before you call anybody.
Three studies, and three completely different conditions
They share one word and nothing else. One prevents nerve damage from chemotherapy, one treats an immune attack on the nerves, and one compares two operations for a trapped nerve.
Stopping Nerve Damage Before It Starts
SWOG Cancer Research Network / Late stage device
This is prevention rather than treatment, and the timing is everything. It is for people about to start certain chemotherapy drugs that often damage the nerves. Wraps cool or squeeze your arms and legs during each infusion, so less drug reaches the hands and feet. Every group gets a real working device, because the three arms differ in what the device does. So there is no dummy and no fake wrap anywhere in it.
Payment is not published.
Check eligibility →More details
Why researchers are excited: numb, burning hands and feet after chemotherapy can last for years, and nothing reliably reverses it. Meanwhile, the only real chance to act is before the first dose.
Who this study is looking for
- A solid tumour, rather than a blood cancer
- Also, starting one of the named chemotherapy plans within three days of joining
- Besides that, no nerve damage already, from any cause
- Finally, able to fill in the forms in English or Spanish
Probably not a fit if: any nerve damage you already have rules you out. So mild tingling from diabetes often ends it at screening. Also, any earlier chemotherapy known to harm nerves, and fingers that go white in the cold.
- Placebo group: None. All three groups wear a real device, and they differ only in cooling and pressure.
- How long: The device is used at every infusion. Nerve checks run to 52 weeks.
- Clinic visits: About 5 study visits, at the start and at weeks 6, 12, 24 and 52. However, the device is used at every chemotherapy session, so each of those appointments runs about an hour longer.
- Phone calls: None published.
- Most invasive part: Nothing added beyond optional blood samples. So the common complaint is simply that the cooling is cold and hard to sit through.
- Setting: Outpatient.
- Where it runs: CaroMont Regional Medical Center, Gastonia NC 28054.
- Drive from Charlotte: Gastonia is about 22 miles west, so roughly half an hour.
- Raise this at the treatment planning visit. The three day window is brutal, and anyone already partway through chemotherapy is too late. So ask before your first dose.
- Full study record: View on ClinicalTrials.gov →
For the Autoimmune Kind, Called CIDP
Janssen / Late stage infusion
CIDP is the kind where your own immune system strips the coating off your nerves. It causes weakness and numbness that build up over weeks or months, in arms and legs. This drug is a drip that lowers the harmful antibodies in your blood. However, the shape of this study is unusual and you need to understand it before calling. The site is inside Charlotte.
Payment is not published.
Check eligibility →More details
Why researchers are excited: the current treatments are steroids and antibody infusions, and neither suits everybody. Meanwhile, a drug that removes the harmful antibodies directly is a different approach.
Who this study is looking for
- CIDP diagnosed by the current criteria, and confirmed again by an outside panel
- Also, A disability score in the study’s range, so ask for your INCAT number
- Besides that, active disease rather than settled disease
- Finally, aged 18 or over, with no upper limit
Probably not a fit if: nerve damage most likely caused by diabetes rules you out. Also, the purely sensory form of CIDP, and several named look alike conditions. Notably, uncontrolled illness elsewhere in the body also excludes.
- Placebo group: Yes, but only in the second stage. Everybody gets the real drug for the first twelve weeks.
- How long: A run in, then twelve weeks on the drug, then up to a further year.
- Clinic visits: Roughly 25 to 40 in person, because the drug is a drip given at the site across more than a year. But treat that as an estimate, since the interval is not published.
- Phone calls: None published.
- Most invasive part: Drips into a vein, and coming off your current treatment first. So people on regular antibody infusions have to stop them to take part.
- Setting: Outpatient.
- Where it runs: The Neurological Institute, Charlotte NC 28204.
- Drive from Charlotte: The site is in Charlotte, off East Morehead Street.
- Ask two questions before anything else. What happens if you get worse during the run in, and what the odds are of being moved to a dummy in the second stage.
- Full study record: View on ClinicalTrials.gov →
Two Real Operations for a Trapped Elbow Nerve
University of Michigan with OrthoCarolina / Surgery study
This is for a nerve squeezed at the inside of the elbow, which numbs the ring and little fingers. Two standard operations exist and surgeons disagree about which is better. So this study settles it by assigning one of the two at random. Both are real, and there is no fake surgery and no group left without an operation. The site is inside Charlotte.
Payment is not published.
Check eligibility →More details
Why researchers are excited: thousands of these operations are done every year with no clear answer on which works better. Meanwhile, both arms here are ordinary care rather than anything experimental.
Who this study is looking for
- Numbness or weakness from the ulnar nerve at the elbow, on its own
- Also, nerve tests confirming it, using set numbers you can ask for
- Besides that, having already tried splinting or other non surgical care
- Finally, able to complete the forms in English
Probably not a fit if: carpal tunnel in the same arm rules you out. That is very common, and it is the usual reason people are turned away here. Also, a previous operation on the same nerve, and a nerve that slips out of place.
- Placebo group: None. Everybody has a real operation, because the two groups are two real techniques.
- How long: A year, with checks at two weeks, six weeks, three months and twelve months.
- Clinic visits: About 6 in person, which are enrolment with the nerve test, the surgery, then two weeks, six weeks, three months and twelve months.
- Phone calls: None published.
- Most invasive part: An operation under anaesthetic, and that is the treatment. Also, nerve tests beforehand, plus grip and sensation testing at each visit.
- Setting: Outpatient.
- Where it runs: OrthoCarolina Research Institute, Charlotte NC 28207.
- Drive from Charlotte: The site is in Charlotte, at OrthoCarolina.
- You do not choose your operation. So be sure you are comfortable with either before you consent. Ask the surgeon to explain both in plain terms.
- Full study record: View on ClinicalTrials.gov →
Not sure which one fits you?
First, answer a few quick health questions. Then we keep them on file. Finally, we tell you which studies near Charlotte you may fit. No account, no paperwork.
See if I may fit one of these studies →What Is Actually Happening in Nerve Damage Research
The word covers several different diseases, and which one you have decides everything that follows.
One Word, Several Different Diseases
Neuropathy just means nerve damage, and it says nothing about the cause. So the numb feet of diabetes, an immune attack on the nerve coating and a trapped nerve at the elbow all carry the same label. Meanwhile, they go to completely different studies. Notably, naming your cause is the single most useful thing you can do before calling anyone.
Most Cases Start at the Feet
The longest nerves reach the toes, so they fail first. That is why it usually begins as numbness or burning in both feet and creeps upwards. So doctors call the pattern stocking and glove, because the hands follow later. In fact, that shape is a clue to the cause on its own.
Diabetes Is the Commonest Cause by Far
Roughly half of people with long standing diabetes develop some nerve damage. So blood sugar control is the treatment as well as the prevention. Meanwhile, the studies open near here do not serve that group, and we would rather say so. However, our nerve pain page covers the studies aimed at the pain it causes.
Ask Whether Anyone Has Looked for a Cause
A real share of cases labelled unexplained turn out to have a treatable cause behind them. Vitamin B12, thyroid, kidney function and a full blood count are the usual first tests. So ask for those by name, because they are ordinary and your own doctor can order them. Also, alcohol and some medicines are common causes people are never asked about.
The Nerve Test Is Not as Bad as It Sounds
A nerve conduction study uses surface pads and small electrical pulses to time your nerves. So it is uncomfortable rather than painful, and it takes under an hour. Meanwhile, its numbers are what several studies gate on. Notably, the elbow study on this page has exact thresholds you can ask about.
Some Nerve Damage Is Preventable
Certain chemotherapy drugs damage nerves in a large share of people who receive them. So one study here tries to stop that happening at all, using cooling and pressure during the infusion. However, it has to start before your first dose, which is a very tight window. In fact, that timing is the whole reason to raise it early.
The Immune Kind Comes On Differently
CIDP is an immune attack on the coating around the nerves, and weakness leads rather than numbness. It builds over weeks or months, and it often affects both sides equally. So it is treatable in a way most nerve damage is not. Meanwhile, being told your case is simply diabetes when it is this is a real and costly mistake.
A Trapped Nerve Is Its Own Category
When one nerve is squeezed at one spot, that is a different problem entirely. The ulnar nerve at the elbow is the classic case, numbing the ring and little fingers. So an operation can fix it, which is not true of most nerve damage. Notably, having carpal tunnel as well rules you out of the study here.
Damage and the Pain It Causes Are Studied Apart
Some studies aim at the nerve damage itself, and others aim only at the pain. So it is worth knowing which you are being offered. Meanwhile, the three studies open near Charlotte are all aimed at the damage. Generally, the pain studies sit on a separate page and have separate rules.
Where Things Actually Stand Locally
Three studies are open around Charlotte, and they are three unrelated conditions. The Midlands has none, and that was checked town by town rather than assumed. So the nearest options for a Columbia patient sit at Union, Greenville and Charleston. However, a second study for the immune kind lists a Charlotte site that has not opened yet.
Nerve Damage Help Near You
Ask what is causing yours, because the answer decides which studies exist for you. Also, ask for the four ordinary blood tests, since some causes are treatable and get missed. Finally, if chemotherapy is coming, raise prevention before your first dose rather than after. Meanwhile, join the list and we will call you when something opens near you.
Research Sites Near Charlotte
OrthoCarolina, The Neurological Institute and CaroMont at Gastonia all run studies in this area. But sites add new studies all the time, so it is worth knowing what is near you.
Atrium Health
Multiple Charlotte locations / 161+ active studies
Crohn’s, Heart Failure, COPD, Dementia, Type 2 Diabetes, Hypertension
Charlotte’s biggest health system. It is tied to Wake Forest University School of Medicine. Also, it runs far more trials than anyone else nearby.
Visit Website →
American Health Research Network
Ballantyne, NC 28277 / 25 to 30+ active studies
Asthma, COPD, Chronic Cough, Type 2 Diabetes
Led by Dr. Selwyn Spangenthal. It is the biggest private lung research group in Charlotte. Specifically, it has 4 offices: Charlotte, Rock Hill, Lake Norman, and Charleston.
Visit Website →
Monroe Biomedical Research
Monroe, NC / 17+ active studies
Asthma, COPD, Hypertension, Obesity, Ulcerative Colitis
Notably, one of the 5 busiest research sites in the country. Its 6,300 sq ft space can host overnight stays. It is also an SCRS Global Impact Partner.
Visit Website →
Clinical Research of Gastonia
Gastonia, NC / 11+ active studies
Asthma, COPD, Chronic Cough, Idiopathic Hypersomnia
Led by Dr. Anup Banerjee. Its 3,500 sq ft space sits next to CaroMont Regional Medical Center. Also, it has been running for over 10 years.
Visit Website →
OnSite Clinical Solutions
Ballantyne, NC 28277 / 10+ active studies
Ulcerative Colitis, Crohn’s, COPD, Heart Failure, Atopic Dermatitis
It works with Charlotte doctors in heart, gut, skin, nerve, and joint care. Besides, it runs studies from Phase I through Phase IV.
Visit Website →
Flourish Research
Matthews, NC 28105 / 4+ active studies
Alzheimer’s Disease, Early Alzheimer’s, Alzheimer’s-Related Psychosis
Led by Dr. M. Reza Bolouri. He has 20+ years in Alzheimer’s research. The site is an Alzheimer’s Center of Excellence. In fact, its network has finished 5,500+ trials.
Visit Website →
New Hope Clinical Research
SouthPark, NC 28211 / 4+ active studies
Major Depression, Schizophrenia, Bipolar Disorder
Led by Dr. Kurian Abraham. It runs Phase I through IV studies and has 30 beds for overnight stays. Its last FDA audit came back clean. Also, it has finished 200+ brain studies.
Visit Website →
Queen City Clinical Research
SouthPark, NC 28211 / 2+ active studies
Chronic Pain, Chronic Migraine, Osteoarthritis
Led by Dr. Leonardo Kapural, a former Cleveland Clinic professor. Notably, he has written 200+ journal articles. On top of that, many call this the biggest pain research site in the country.
Visit Website →
Novant Health
Multiple Charlotte locations / Several active studies
Cardiovascular Disease, Obesity, Hypertension
One of the biggest health systems in the Carolinas. Its Heart and Vascular Institute runs heart studies and sees a lot of patients.
Visit Website →
DLVSC
4 Charlotte-area offices / 1+ active studies
Eczema, Psoriasis, Rosacea
Led by Dr. Gilly Munavalli. This award-winning skin practice owns 50+ FDA-approved lasers and devices. Also, it has its own research team.
Visit Website →
DelRicht Research
South Charlotte, NC 28210 / 1+ active studies
Bipolar Disorder, Bipolar Depression
Part of a national network of mental health research sites. Currently, it runs the azetukalner bipolar depression trial in Charlotte. Previously, it ran other mental health studies.
Visit Website →
TMS of the Carolinas
South Charlotte, NC 28210 / 1+ active studies
Major Depression, Treatment-Resistant Depression
A specialty site for brain stimulation care. It runs the fast TMS study that packs 6 weeks into 2.
Visit Website →What to Expect in a Nerve Study
New to studies? Here is how one works, step by step.
01
Prescreening
First comes a short phone call or online form. Also, it takes about 10 to 15 minutes. The staff check whether you might fit. Then they tell you what is open.
02
Screening Visit
Next the clinic runs the tests that decide it, which usually means blood work. Also, they go through the consent form line by line, and you can bring somebody with you.
03
Treatment Period
Then the study begins. So you take the study drug or the placebo on the agreed schedule. Meanwhile, your own doctor keeps managing everything else.
04
Follow-Up
Finally, there is a check in period at the end. Also, your own doctor gets the results, and you can stop at any point without affecting your care.
Neuropathy Trial FAQs
Real answers about nerve damage studies near Charlotte NC.
Is there a study for this near Charlotte?
Yes, three, and they are three different conditions. One prevents nerve damage in people about to start certain chemotherapy. One treats an immune attack on the nerve coating, called CIDP. One compares two operations for a nerve trapped at the elbow. However, none of them is for nerve damage caused by diabetes.
Does neuropathy mean one thing?
No, and that is the most useful thing to know here. It just means nerve damage, and it says nothing about the cause. So the numb feet of diabetes, an immune attack on the nerve coating and a trapped nerve at the elbow all carry the same label. Meanwhile, they go to completely different studies.
Why does it start in my feet?
Because the longest nerves reach the toes, so they fail first. That is why it usually begins as numbness or burning in both feet and creeps upwards over time. So doctors call the pattern stocking and glove, since the hands follow later. In fact, that shape is a clue to the cause on its own.
Is there anything for nerve damage from diabetes?
Not on this page, and we would rather say that plainly. The studies open near here are for chemotherapy prevention, for an immune form, and for a trapped nerve at the elbow. So none of them serves the commonest cause. However, our nerve pain page covers the studies aimed at the pain that diabetes causes, and there is one near Charlotte.
Which blood tests should I ask for?
Four of them, and your own doctor can order all four. Vitamin B12, thyroid, kidney function and a full blood count. So those cover a real share of the causes that get missed. Also, alcohol and certain medicines are common causes that people are simply never asked about.
What is a nerve conduction study like?
Surface pads and small electrical pulses time how fast your nerves carry signals. So it is uncomfortable rather than painful, and it usually takes under an hour. Meanwhile, its numbers are what several studies gate on. Notably, the elbow study near Charlotte has exact thresholds you can ask about by name.
Can nerve damage from chemotherapy be prevented?
That is exactly what one nearby study is testing, using cooling and pressure wraps during each infusion. Every group wears a real working device, so there is no dummy in it. However, it has to begin within three days of your first chemotherapy dose. So raise it at the treatment planning visit rather than afterwards, because afterwards is too late.
Does it cost anything to check?
No. There is no cost, and no insurance is needed. Tether is a nonprofit list, so we do not run studies and we are not paid to send you anywhere. Also, checking never enrolls anyone in anything. You would always call the clinic yourself.
Where can I get help near Charlotte?
Atrium Health and Novant Health both run neurology services across the metro, and The Neurological Institute is a specialist practice here. Also, ask what is causing your nerve damage, because the answer decides which studies exist for you. Generally, your own doctor can order the first blood tests. Meanwhile, ask about a nerve conduction study if nobody has arranged one.
Ready to Explore a Study?
Check your eligibility, or just reach out to our Charlotte team. No pressure. Also, no sales pitch.
← Back to All Clinical TrialsSources
- ICE COMPRESS, preventing nerve damage during chemotherapy, ClinicalTrials.gov NCT05642611
- A drip study for the autoimmune kind, inside Charlotte, ClinicalTrials.gov NCT05327114
- SUN, comparing two operations for a trapped elbow nerve, ClinicalTrials.gov NCT04254185
- ACT-EARLY, a prevention study for gene carriers, ClinicalTrials.gov NCT06563895
- A second study for the autoimmune kind, listing a Charlotte site not yet open, ClinicalTrials.gov NCT07032662
Study details and per-site recruiting status verified against ClinicalTrials.gov on August 17, 2026. The three studies near Charlotte are three unrelated conditions that share one word, and none of them serves nerve damage caused by diabetes, which is the commonest cause by a wide margin. A second study for the immune form lists a Charlotte site, but that row has not opened yet, so it is named as a watch item rather than published as an option. The Columbia zero was checked town by town, and separately for the small fibre, inherited and chemotherapy related forms. Six searches on the word Columbia returned sites in New York, Missouri and Maryland instead. Study availability and criteria change; the research clinic confirms everything before you enroll.